Gene Expression
Explore the mechanisms and processes that regulate gene expression, including transcriptional and post-transcriptional controls, epigenetic modifications, and their roles in cancer development and potential targeted therapies.
Introduction to Gene Expression
Regulation of Gene Expression
Prokaryotic Versus Eukaryotic Gene Expression
Summarizing Regulation of Gene Expression
Prokaryotic Gene Regulation
The <em>trp</em> Operon: A Repressor Operon
Catabolite Activator Protein (CAP): An Activator Regulator
The <em>lac</em> Operon: An Inducer Operon
Summarizing Prokaryotic Gene Regulation
Epigenetic Control: Regulating Access to Genes Within the Chromosome
Summarizing Eukaryotic Epigenetic Gene Regulation
Eukaryotic Transcription Gene Regulation
The Promoter and the Transcription Machinery
Enhancers, Transcription and Transcriptional Repressors
Summarizing Eukaryotic Transcription Gene Regulation
RNA Splicing, the First Stage of Post-transcriptional Control
Control of RNA Stability
Summarizing Eukaryotic Post-transcriptional Gene Regulation
The Initiation Complex and Translation Rate
Chemical Modifications, Protein Activity, and Longevity
Summarizing Eukaryotic Translational and Post-Translational Gene Regulation
Cancer and Gene Regulation
Cancer: Disease of Altered Gene Expression
Cancer and Epigenetic Alterations
Cancer and Transcriptional Control
Cancer and Post-Transcriptional Control
Cancer and Translational/Post-Translational Control
New Drugs to Combat Cancer: Targeted Therapies
Summarizing Cancer and Gene Regulation