<h2>Summary</h2>
<p>In eukaryotic cells, the first stage of <a href="https://app.ulearngo.com/tutorials/introducing-genetics/gene-expression-2">gene expression</a> control occurs at the epigenetic level. Epigenetic mechanisms control access to the chromosomal region to allow genes to be turned on or off. These mechanisms control how DNA is packed into the nucleus by regulating how tightly the DNA is wound around histone proteins. The addition or removal of chemical modifications (or flags) to histone proteins or DNA signals to the cell to open or close a chromosomal region. Therefore, eukaryotic cells can control whether a gene is expressed by controlling accessibility to transcription factors and the binding of <a href="https://app.ulearngo.com/tutorials/introducing-genetics/rna">RNA</a> polymerase to initiate transcription.</p>
<h2>Glossary</h2>
<h3>transcription factor</h3>
<p>protein that binds to the DNA at the promoter or enhancer region and that influences transcription of a gene</p>

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Summarizing Eukaryotic Epigenetic Gene Regulation

Biology studies life and living organisms. Biology can be divided into different sections that cover the morphology, physiology, anatomy, behavior, and so on of living organisms.

Biology

Explore the mechanisms and processes that regulate gene expression, including transcriptional and post-transcriptional controls, epigenetic modifications, and their roles in cancer development and potential targeted therapies.


Gene Expression

Summarizing Eukaryotic Epigenetic Gene Regulation

Summary

Glossary

transcription factor

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